Chromogranin a level
WebBackground: Chromogranin A (CgA) has been shown to be a useful marker in the diagnosis of neuroendocrine (NE) tumours. The clinical significance of CgA has been … WebOct 17, 2015 · A blood tumor marker used for detection of certain cancers. Chromogranin A is considered the best general neuroendocrine serum or plasma marker available both …
Chromogranin a level
Did you know?
WebChromogranin A is a protein stored and released with peptides and amines in a variety of neuroendocrine tissues. The plasma level of chromogranin A in patients with neuroendocrine tumors has a sensitivity and specificity of 75% and 84%, respectively. Chromogranin A levels increase with tumor burden. WebChromogranin A is a secretory protein. It is located in the large, dense-core vesicles of neuroendocrine cells. Chromogranin A-derived peptides are involved in a range of …
WebMay 20, 2007 · It is necessary to use a cutoff range of 84 to 87 U/L to obtain a high specificity in diagnosing NETs, with the aim of excluding patients in whom the CgA was elevated as a result of other non-neoplastic … Our study confirms the high specificity and sensitivity of CgA in diagnosing an endocrine tumor. WebSep 24, 2024 · Chromogranin A is a secretory protein, composed of 439 amino acids, found in the large dense-core vesicles of the neuroendocrine cells. It belongs to the …
WebApr 24, 2024 · It would be a good idea to inquire if your doctor would do these lab tests as well. From what my GI doctor has told me that the Chromogranin A Level can be high if … WebSep 21, 2016 · Chromogranin A (CgA) is an acidic glycoprotein with a molecular mass of 49 kd that is widely expressed by neuroendocrine cells and constitutes one of the most abundant components of secretory granules. 1 CgA is physiologically released by exocytosis and may be detected in the blood.
WebNational Center for Biotechnology Information
WebTypically, chromogranin A levels are around 2.5 times higher with the LC/MS/MS assay—this relationship is captured by the following equation: ELISA result = 13.6 + 0.36 … concrete garage pitched roofWebTypically, chromogranin A levels are around 2.5 times higher with the LC/MS/MS assay—this relationship is captured by the following equation: ELISA result = 13.6 + 0.36 × LC/MS/MS result; correlation coefficient = 0.71. Reference intervals … ectas online helpWebChromogranin A (CGA) is a 439-amino acid protein with a molecular weight of 48 to 60 kDa, depending on glycosylation and phosphorylation status. It is a member of the granin family of proteins and polypeptides. ectasis words ending meaningWebJul 27, 2013 · Hi Everyone, Thanks for all the infomation on makers. I'm going to assume Chromogranin A has value since I have just gotten the results of a Ga-68 PET scan that revealed 3 liver mets and lymph node invasion. My levels remained unchanged before and after removal of the primary tumor from the pancreas in December 2012. ectasia of the common iliac arteries icd 10concrete garage floor finishing optionsWebAbstract. Chromogranin A (CgA) not only plays an important role in pathologic diagnosis, but is also used as a circulating biomarker in patients with gastroenteropancreatic neuroendocrine neoplasm (GEP-NEN). However, the relationship between immunohistochemistry (IHC) expression and serum levels of CgA has not been … concrete front porch stairs ideasWebJul 20, 2024 · A 100% elevation of CgA is seen in gastrinomas, 89% in pheochromocytomas, 80% in neuroendocrine tumors of the small intestine, 69% in … ectasis medical terminology examples