WebDec 6, 2024 · Interestingly, the translation initiation of CHSY1 was suppressed by a highly structured sequence (positions -202 to -117 relative to the initiation codon) containing RNA G-quadruplex (G4) structures in 5'-untranslated region. WebDec 1, 2010 · CHSY1 encodes a type II transmembrane protein comprising a Fringe motif and a glycosyltransferase domain. CHSY1 was found to be secreted, and functional experiments carried out in patients' cells, human fetal osteoblasts cells, and gliobastoma cells revealed remarkable NOTCH upregulation in the absence of CHSY1 activity.
A novel CHSY1 gene mutation underlies Temtamy preaxial brachydactyly ...
WebImmunohistochemical analysis of paraffin-embedded human lung cancer using 14420-1-AP (CHSY1 antibody) at dilution of 1:100 (under 40x lens). View All Images (4) Save time and replace your secondary antibodies with our FlexAble Antibody Labeling Kits $389 / 150 μL Cat No. 14420-1-AP In stock. WebCHSY1 Antibody (14420-1-AP) in IHC (P) Immunohistochemistry of paraffin-embedded human lung cancer using 14420-1-AP (CHSY1 antibody) at dilution of 1:100 (under 40x lens). Product Details Product Specific Information shanu jagernath
Loss of CHSY1, a Secreted FRINGE Enzyme, Causes
WebNov 1, 2010 · High-throughput sequencing of all 177 candidate genes detected a disease-causing frameshift mutation in the gene CHSY1 encoding for a chondroitin synthase with … WebJan 1, 2014 · The Fringe-like domain in CHSY1 shares 47 % amino acid similarity with Fringe, and it also has the key DXD motif. Modulation of Notch signaling by CHSY1 via its DXD motif may provide new insight into the interaction mechanisms between myeloma cells and their bone marrow microenvironment. WebCHSY1 Family name : Chondroitin N-acetylgalactosaminyltransferase Entry whose protein (s) existence is based on evidence at protein level. Show evidences Annotations in this section apply to all the isoforms if not specified otherwise. OVERVIEW Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. shanu cnc components industry