Cisplatin or carboplatin
WebMar 30, 2024 · FDA approves durvalumab for extensive-stage small cell lung cancer On March 27, 2024, the Food and Drug Administration approved durvalumab (IMFINZI, AstraZeneca) in combination with etoposide and... WebApr 10, 2024 · Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, …
Cisplatin or carboplatin
Did you know?
WebCarboplatin / pharmacology Cisplatin / metabolism Cisplatin / pharmacology* Cisplatin / therapeutic use DNA / drug effects Drug Resistance / genetics Gene Expression Regulation, Neoplastic / drug effects ... WebUsually, the combination includes a type of chemo drug called a platinum compound (usually cisplatin or carboplatin), and another type of chemo drug called a taxane, such as paclitaxel (Taxol ®) or docetaxel (Taxotere ® ). These drugs are usually given as an IV (put into a vein) every 3 to 4 weeks.
WebFeb 28, 2024 · The EP regimen (etoposide plus cisplatin), in particular, is the most frequently used chemotherapy regimen for initial treatment. 4 Carboplatin is also frequently used clinically as a replacement of cisplatin to reduce vomiting, neurotoxicity, and … WebFeb 28, 2024 · The EP regimen (etoposide plus cisplatin), in particular, is the most frequently used chemotherapy regimen for initial treatment.4Carboplatin is also frequently used clinically as a replacement of cisplatin to reduce vomiting, neurotoxicity, and nephrotoxicity, but similarly it increases the risk of myelosuppression.
WebWe investigated the activity and safety of first-line GEMOX compared with gemcitabine–carboplatin (GCb) in cisplatin-ineligible patients with advanced UCC. Methods: Treatment-naive, cisplatin-ineligible patients with advanced UCC were randomly assigned to GEMOX (gemcitabine 1000 mg/m 2 , oxaliplatin 100 mg/m 2 on day 1 [D1] … WebMay 10, 2012 · Carboplatin- or cisplatin-based chemotherapy in first-line treatment of small-cell lung cancer: the COCIS meta-analysis of individual patient data. Our meta-analysis of individual patient data suggests no differences in efficacy between cisplatin …
WebCisplatin and carboplatin based combinations are not used as an initial therapy. The indications for these two drugs are primary resistant malignant lymphoma and multiple myeloma, or relapses of these diseases not responding to conventional therapy.
WebNov 5, 2024 · The primary objective is to assess the pathological complete response rate (ypT0) in each cohort and independently of a combination therapy with neoadjuvant durvalumab and chemotherapy (Gemcitabine/Cisplatin) before surgery in patients with high-risk, localized, non-metastatic urothelial carcinomas of the upper tract.Secondary … razor new selectlistWebMar 23, 2015 · The recommendation to administer gemcitabine prior to cisplatin is based on results of phase 1 studies in adults with solid tumors, which indicated that this administration schedule may increase... razor new laptop carrying caseWebAug 19, 2007 · And the reason most oncologists feel that carboplatin is the best choice is that if there is a difference, it's a slight one, felt to be more than offset by the toxicities and inconveniences of cisplatin compared to carboplatin, including considerably more … razor nick infectionWebJul 1, 2000 · Carboplatin provides an improved therapeutic index compared to cisplatin, especially in terms of reduced nonhematologic toxicities. However, added hematologic toxicity may be problematic when combining carboplatin with other myelosuppressive chemotherapeutic agents. razor new laptop 3 screenWebPembrolizumab was approved for use in combination with platinum and fluorouracil (FU) for all patients and as a single agent for patients whose tumors express PD‑L1 (Combined Positive Score [CPS]... razor night eye themeWebHowever, the toxicity of carboplatin was smaller than that of cisplatin in proximal tubular epithelial cells that had been preincubated with AGEs. Yokoo et al reported that carboplatin is not transported by organic cation transporter and MATE1/SLC47A1; 29 thus, the … razor not chargingWebExperiences with cisplatin and carboplatin are summarized in this paper. The treatment response to monotherapy with cisplatin or carboplatin was proved in non-Hodgkin's lymphomas. This is necessary condition for the application of the drug in … simpson strong tie timber strap esr