Web29. sep 2024 · The biochemical parameters of all 79 participants were evaluated, and the results were as follows: ferritin 443 ± 47 μg/L, TS% 34.0 ± 2.0%, and hemoglobin 13.2 ± 0.2 g/dL (values are expressed as the mean ± standard error). These participants were then divided into two groups based on their genotypes. WebPheWAS-ME helps subject-matter experts parse through the results of a PheWAS analysis by letting them isolate and explore specific subsets of phenotypes by looking not only at their p-values and effects-sizes but also by the subject-level data that generated those results. ... Annual review of genomics and human genetics 17, (2016), 353–373 ...
MR-pheWAS with stratification and interaction: Searching for the …
WebUniversity of Utah School of Medicine. 2015년 9월 - 2024년 2월6년 6개월. Greater Salt Lake City Area. For decades, high throughput technologies have successfully captured diverse genome-wide sequence information, quantitative gene expression, and regulatory information. The generation of huge volumes of data by these technologies ... Web15. jún 2024 · With the advances in genotyping technologies and electronic health records (EHRs), large biobanks have been great resources to identify novel genetic associations … brent huntley las vegas
PheWAS - Phenome Wide Association Studies
WebVolume 162, June 2024, Pages 1-10 Author links open overlay panel, , Abstract. Schizophrenia is a chronic debilitating psychiatric disorder with significant morbidity and mortality. In this study, we used information from 337,484 UK Biobank participants and performed PheWAS using schizophrenia genetic risk score on 1135 disease outcomes. WebStavroula Kanoni, Sarah E. Graham, Yuxuan Wang, Ida Surakka, Shweta Ramdas, Xiang Zhu, Shoa L. Clarke, Konain Fatima Bhatti, Sailaja Vedantam, Thomas W. Winkler, Adam ... WebGenome-wide association studies (GWASs) require accurate cohort phenotyping, but expert labeling can be costly, time intensive, and variable. Here, we develop a machine learning (ML) model to predict glaucomatous optic nerve head features from color fundus photographs. We used the model to predict vertical cup-to-disc ratio (VCDR), a diagnostic … brent huntley qb