Toxicities of 166holmium-chitosan in mice

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WebLee, W.Y. et al. Toxicities of 166Holmium-chitosan in mice. Arzneimittelforschung 48 , 300–304 ( 1998). CAS PubMed Google Scholar WebNov 21, 2014 · 2.4. Chronic toxicity assay of chitosan and its derivates in in vivo models. Chronic toxicity studies were carried out with chitosan and modified chitosan materials after peroral treatment at a dose of 30 mg kg −1 bw per day in Swiss albino mice. Experimental animals were divided into the following seven groups (n = 6).

A pilot study of trans-arterial injection of 166Holmium-Chitosan ...

WebMar 1, 1998 · In this study, 166Ho was complexed to chitosan (Chit) which decreases the distribution of Ho into other tissues when applied intrahepatically. To investigate the … http://allie.dbcls.jp/pair/166Ho;166Holmium.html how to set google as main browser edge

Pulmonary Application of Novel Antigen-Loaded Chitosan Nano …

WebResults: After administration of 166Ho-chitosan complex, the radioactive concentrations in blood were low, and cumulative urinary and fecal excretions over a period of 0-72 hr were … WebApr 1, 2010 · The single dose toxicity of chitosan in rodents is low with reported values given in Table 3. This table also summarises repeat dose toxicity studies that have been performed with chitosan or related materials in rodents, rabbits and dogs using various parenteral and oral (gavage and dietary) routes. Web166 Holmium-Chitosan complex, in which chitosan is chelated with 166 Holmium, was developed as a radiopharmaceutical for cancer therapy. We have conducted a pilot study to evaluate the clinical efficacy of transarterial administration of 166 Holmium-Chitosan complex in patients with a single and small (< 3 cm) hepatocellular carcinoma. 166 note s8 akg earbuds review

Chitosan induced hepato-nephrotoxicity in mice with …

166Holmium (166Ho) - Allie: Abbreviation / Long Form Info.

WebApr 1, 2013 · The toxicity of chitosan nanoparticles needs to be evaluated in embryo development aspects because extensive research into their biomedical applications was based largely on the biodegradable and biocompatible profile of chitosan. ... The mice were housed in wire cages at 22 ± 1°C under a 12L:12D cycle with 70% humidity and fed ad … WebFeb 1, 2012 · Chitosan cause loss of fat-soluble vitamins and block absorption of medicines such as birth control pills (Orr, 1999).This study was designed to investigate the hepato … how to set google as main browser windows 10WebOverall, the results suggested that the oral administration of the derivatives of chitosan in mice did not produce any significant toxicity in chronic treatment. Hence, these polymers … how to set google as homepage on chrome

"WebAug 2, 2015 · Chitosan, an excellent biomedical material, has received a widespread in vivo application. In contrast, its metabolism and distribution once being implanted were less documented. In this study, the pharmacokinetics and biodegradation of fluorescein isothiocyanate (FITC) labeled and muscle implantation administrated chitosan in rats … " - Toxicities of 166holmium-chitosan in mice

Toxicities of 166holmium-chitosan in mice

Chitosan Nanoparticles Cause Pre- and Postimplantation Embryo ...

WebTo investigate the single dose toxicity, mice were administered intravenously with 1 mCi/kg body weight of 166Ho-Chit (DW-166HC), Chit or nothing. Organ weights, hematological … WebNov 7, 2024 · As in the rodent model, Huh et al. have reported that 166 Ho chitosan complex can be used for the treatment of malignant glioma in mice model when injected at the …

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WebAbbreviation / Long Form : 166Ho / 166Holmium [Related PubMed/MEDLINE] Total Number of Papers: 1 [Entries Per Page] per page Page Control Page: of : Abbreviation: 166Ho (>> Co-occurring Abbreviation) Long Form: ... Toxicities of 166Holmium-chitosan in mice. WebMar 9, 2024 · In vivo toxicity evaluation of tumor targeted glycol chitosan nanoparticles in healthy mice: repeated high-dose of glycol chitosan nanoparticles potentially induce cardiotoxicity This study demonstrates that repeated high-dose CNPs induce severe cardiotoxicity in vivo.

WebFeb 5, 2024 · The term mushroom refers to the fungal fruiting body. Anatomically, the prototypical mushroom comprises the stem and a cap with gills on the underside. However, the term may refer to many … WebDec 1, 2005 · The fate of 166Ho-chitosan complex, a radiopharmaceutical drug for cancer therapy, was determined by studying its absorption, distribution and excretion in rats and …

WebJan 31, 2010 · No oral toxicity was found in mice treated with 100 mg/kg chitosan nanoparticles (80 kDa, 80% DD) [81]. There was slight toxicity at high dose observed in … WebChitosan is an antilipidemic dietary supplement used as a diet aide. The present study investigated the effect of sex-toxicity relationship between male and female mice orally …

WebJun 8, 2024 · In vivo toxicities of TP and CCTP were compared by using normal BALB/c mice that were evaluated by monitoring body weight change and hematological toxicity . Previous experiments showed that the minimum lethal dose of mice was about 0.5 mg TP/kg. Here, a safe dose of free TP of 0.2 mg/kg was adopted for mice in toxicity assay.

WebApr 1, 2024 · The holmium/chitosan complex (Millican, Dong Wha Pharmaceutical Co., Seoul, Korea) was effective in treating small HCCs in a novel study based on 40 patients with single HCC < 3 cm in size with... note s8WebApr 13, 2024 · The chitosan-coated nanoemulsions with TMZ showed the expected physicochemical characteristics and demonstrated safety and efficacy, reducing around 70% the tumor size compared to control mice, and presenting a tendency in mitotic index reduction, becoming an interesting approach to treat melanoma brain metastasis. ... To … how to set google as new tab in edgeWebSep 20, 2024 · This study assessed the protective effects of selenium-chitosan (SC) against antioxidant and immune function-related damage induced by zearalenone (ZEN) in mice. In total, 150 female mice were allotted to five groups for a 30-day study. Control mice were fed a basal diet. Mice in the ZEN, ZEN-Se1, ZEN-Se2 and ZEN-Se3 groups were fed the basal … note save onlineWebApr 13, 2024 · The most successful medical intervention for preventing infectious diseases is still vaccination. This effective strategy has resulted in decreased mortality and extended life expectancy. However, there is still a critical need for novel vaccination strategies and vaccines. Antigen cargo delivery by nanoparticle-based carriers could promote superior … how to set google as primary browserWebJul 9, 2024 · Chitosan possesses a high density of positive charges due to the protonation of amino groups and presents properties such as nontoxicity, biocompatibility and biodegradability (Luo and Wang, 2014 ). how to set google as new tab page in edgeWebJin Lee's 3 research works with 9 citations and 24 reads, including: Toxicities of 166Holmium-chitosan in mice how to set google as standard browserWebDec 10, 2024 · This study was conducted to evaluate the subacute toxicity effect of Chitosan-alginate coated microparticle of Garcinia mangostana Linn extract’s oral administration. Fifty BALB/c mice were... how to set google as main search browser