Ttf 1 antibody

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August undefined, 2024

WebOct 24, 2024 · Objectives: Immunohistochemical staining against thyroid transcription factor 1 (TTF-1) is often used to distinguish lung adenocarcinoma from squamous cell carcinoma and pulmonary metastasis. Methods: TTF-1 expression was examined using the antibody clones 8G7G3/1, SPT24, and SP141 on tissue microarrays from 665 cases of resected … WebGeneral description. Anti-TTF-1 (Thyroid Transcription Factor 1) is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the organs rather than thyroid 1-2, germ cell tumors 3, and malignant mesothelioma. 4-5 It can also be used to differentiate small cell lung carcinoma from lymphoid ...

Comparison of Three Different TTF-1 Clones in Resected Primary …

WebTTF-1 (thyroid transcripton factor-1, NKX2.1) is a homeodomain-containing transcription factor. It controls cell differentiation of telencephalic cells and is essential for proper ventral forebrain development. Furthermore, it is a key factor in the morphogenesis and differentiation of the thyroid and lung. TTF-1 is detected in primary lung adenocarcinomas … dyson dc59 cleaning instructions

TTF-1 Antibody - Biocare Medical

WebTTF-1 has been identified as a transcriptional regulator of thyroid-specific genes and has also been shown to be important in the activation of pulmonary-specific differentiation genes. Monoclonal anti-rat TTF-1 clone 8G7G3/1 (anti-TTF-1) has also been shown to react with rat, mouse and human TTF-1. Primary Antibody WebPolyclonal Antibody for studying TTF-1 (Ser327) phosphate. Cited in 1 publication. Validated for Western Blotting, Immunoprecipitation. Highly specific and rigorously validated in-house, Phospho-TTF-1 (Ser327) Antibody (CST #13608) is ready to ship. WebMonoclonal antibody is produced by immunizing animals with a recombinant protein corresponding to a 123 amino acid fragment of the N-terminal region of human TTF-1 protein. Background Thyroid Transcription Factor 1 (TTF-1, also known as NKX2-1), a member of the NKX homeobox transcription factor family, was initially discovered in the … dyson dc59 motorhead vacuum battery

Thyroid Transcription Factor 1 (TTF-1) (SPT24) Mouse mAb

Anti-TTF-1 Antibody serum, Upstate® Sigma-Aldrich

WebTTF1 Antibody (MA5-31938) in ICC/IF. Immunocytochemistry analysis of TTF1 in SK-OV-3 cells (green). Sample was incubated with TTF1 monoclonal antibody ( Product # MA5-31938) using a dilution of 1:200-1:1000 followed by DRAQ5 fluorescent DNA dye (blue), and Alexa Fluor- 555 phalloidin (red labeled actin filaments) . WebFor immunohistochemistry, the antibody is ready-to-use. Application Notes The BioLegend TTF-1 (8G7G3/1) antibody recognizes the 40kD thyroid transcription factor, which is a member of the NKx2 family of transcription factors. TTF-1 antigen is expressed in epithelial cells of the thyroid gland and the lung. RRID csc vaishaliWeb15 rows · Dec 10, 2016 · TTF-1 Antibody (H-190) is a rabbit polyclonal IgG; 200 µg/ml; epitope corresponding to amino acids 1-190 mapping at the N-terminus of TTF-1 of … dyson dc59 motorhead refurbished

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Ttf 1 antibody

WebThe antibody cocktail of TTF-1 + Napsin A has demonstrated a sensitivity of 91% (105/115) for lung ADC and 95% specificity (5/95) versus lung SCC (2). In cases where TTF-1 and Napsin A are both positive, specificity versus lung squamous cell carcinoma has been shown to be 100% (2). Specifications. WebDetection of Human TTF-1/NKX2-1 by Western Blot. Western blot shows lysates of TT human medullary thyroid cancer cell line. PVDF membrane was probed with 1 µg/mL of …

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WebApr 14, 2024 · A Dual Antibody Fetal Cell Count Kit includes antibodies for hemoglobin F (HbF) and carbonic ... and is often multifocal. Positive TTF-1 staining is useful in establishing pulmonary origin and targeted immunostains can be used to rule out possible metastatic disease (CDX2 was used in this case to rule out an intestinal primary ... WebAnti-TTF-1 Antibody is a high quality Rabbit Polyclonal Antibody for the detection of TTF-1 & has been validated in IP, WB & IHC. FUNCTION: SwissProt: P43699 # Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor.

WebIndependently Validated Antibody, image provided by Science Direct, badge number 028752. Western blot analysis of mouse brain and liver extracts using NK2 Homeobox 1 (bs-0826R NKX2-1) antibody, 1:500 dilution. NKX2-1 is present in the positive control sample (brain) and absent from the negative control sample (liver). WebPolyclonal Antibody for studying TTF-1 (Ser327) phosphate. Cited in 1 publication. Validated for Western Blotting, Immunoprecipitation. Highly specific and rigorously validated in …

WebTTF-1 antibody is useful in differentiating primary Adenocarcinoma of the Lung from Metastatic Carcinomas of the breast and Malignant Mesothelioma. It can also be used to … WebTTF1 is a transcription termination factor that is localized to the nucleolus and plays a critical role in ribosomal gene transcription. The protein mediates the termination of RNA polymerase I transcription by binding to Sal box terminator elements downstream of pre-rRNA coding regions. For Research Use Only. Not for use in diagnostic procedures.

WebThe sections were incubated for 1 hour with the monoclonal mouse antibody specific for TTF-1 (clone 8G7G3/1, Santa Cruz, USA) at a dilution of 1 : 100, then washed with PBS solution (pH 7.4), and incubated for 30 minutes at 37°C with the secondary antibody (catalog: PV-8000, Zhongshan Co., itd, China), which is a biotin-free detection system that …

WebIdentifies the 40 kDa TTF-1 band in nuclear extracts or whole cell lysates of TTF-1-positive cell lines of rat, mouse and man. TTF-1 is selectively expressed in lung and thyroid, and … csc vacation policyWebTTF-1 antibody; TTF1 antibody; see all. Images. Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TTF1 antibody [8G7G3/1] (ab233977) Formalin-fixed, … csc version 2.0.6WebAnti-TTF-1 Antibody is a high quality Rabbit Polyclonal Antibody for the detection of TTF-1 & has been validated in IP, WB & IHC. Research Category Epigenetics & Nuclear Function. Research Sub Category Transcription Factors. Quality. routinely evaluated by immunoblot on nuclear extract from H441 human lung epithelial cells. cscvf01652WebSep 16, 2024 · Definition / general. Thyroid transcription factor 1, also known as NKX2-1 or thyroid specific enhancer binding protein. Homeodomain containing transcription factor, member of the NKX2 gene … cscu workshopsWebSep 3, 2024 · western blot; human; fig 1 Chen P, Wu T, Cheng Y, Chen C, Lee H. NKX2-1-mediated p53 expression modulates lung adenocarcinoma progression via modulating IKKβ/NF-κB activation. Oncotarget. 2015;6:14274-89 pubmed csc valy statusWebThe thyroid transcription factor 1 (TTF-1) is a homeodomain-containing transcription factor that activates the transcriptional activity of thyroid-specific gene promoters by binding to them. Hence, TTF-1 is crucial in the maintenance of the thyroid differentiation phenotype (1). Thyroid dysgenesis (TD) is responsible for most cases of ... dyson dc59 rear soleplateWebMar 5, 2024 · TTF-1 Antibody (8G7G3/1) is an IgG 1 κ mouse monoclonal TTF-1 antibody (also designated TTF1 antibody) that detects the TTF-1 protein of mouse, rat and human … dyson dc56 battery life